Table 1.
Brodmann areas and MNI coordinates of activations to CS+ vs. CS− during the early and late acquisition and extinction phase
MNI coordinate |
|||||||
---|---|---|---|---|---|---|---|
Brain region (and hemisphere) | BA | Cluster size (number of voxels) | Z-value | x | y | z | P-value |
Early acquisition | |||||||
Posterior hippocampus (L) | 23 | 3.48 | −33 | −36 | −6 | < 0.05* | |
Late acquisition | |||||||
Inferior frontal gyrus (R) | BA9/47 | 737 | 5.56 | 54 | 18 | 0 | < 0.05 |
Insula (R) | BA13 | 110 | 4.71 | −39 | 21 | 0 | < 0.05 |
Medial superior frontal gyrus (R) | BA8 | 67 | 4.42 | 3 | 33 | 51 | < 0.05 |
Supramarginal gyrus (R) | BA40 | 332 | 4.77 | 66 | −36 | 39 | < 0.05 |
Ventral putamen (L) extending to amygdala | 218 | 4.58 | −30 | −3 | −9 | < 0.05 | |
Amygdala (L) | 24 | 4.22 | −30 | −3 | −12 | < 0.05* | |
Dorsal hippocampus (L) | 12 | 3.11 | −36 | −21 | −9 | < 0.05* | |
Primary somatosensory cortex (L) | BA40 | 132 | 3.99 | −57 | −30 | 48 | < 0.05 |
Extinction | |||||||
Superior frontal gyrus (R) | BA10 | 47 | 3.15 | 36 | 54 | 15 | < 0.05 |
Superior frontal gyrus (L) | BA10 | 34 | 3.08 | −18 | 48 | 15 | < 0.05 |
Dorsal anterior cingulate (R) | BA32 | 15 | 2.98 | 12 | 36 | 24 | < 0.05* |
L, left hemisphere; R, right hemisphere; BA, Brodmann area; MNI, Montreal Neurological Institute.
FDR-corrected for the ROI.