Table 1.
Characteristics | Controls (N = 25) | COPD (N = 29) | p-value |
---|---|---|---|
Age/yrs mean (SD) | 64.8 (6.8) | 69.1 (9.8) | 0.137 |
Height/cms | 164.3 (9.3) | 164.8 (9.2) | 0.849 |
Gender: Male N (%) | 16 (64) | 23 (79) | 0.218 |
Ethnicity N (%)* | 0.061 | ||
East Indians (Indo-Trinidadian) | 9 (36) | 16 (55) | |
African (Afro-Trinidadian) | 8 (32) | 10 (35) | |
Other | 8 (32) | 3 (10) | |
BMI kg/m2 (median (IQR) | 27.4 (25.9, 29.9) | 24.0 (20.5, 27.0) | 0.001 |
Lung Function (mean (SD)) | |||
FEV1/L | 2.25 (0.77) | 1.43 (0.60) | <0.001 |
FVC/L | 2.91 (1.02) | 2.72 (0.82) | 0.18 |
FEV1/FVC % | 78.1 (8.3) | 53.1 (14.0) | <0.001 |
FEV1 % predicted | 76.1 (17.2) | 49.1 (16.3) | <0.001 |
SGRQ Scores (median (IQR)) | |||
Impact | 0.0 (0.0, 0.0) | 35.7 (10.0, 50.8) | <0.001 |
Activity | 6.2 (0.0,12.2) | 47.7 (26.0, 66.3) | <0.001 |
Symptoms | 0.0 (0.0,8.1) | 49.3 (19.1, 64.0) | <0.001 |
Total | 2.8 (0.0, 9.3) | 44.2 (18.4, 55.0) | <0.001 |
tHCY/micromol/L | 8.22 (6.63, 9.55) | 10.96 (7.56,13.60) | 0.006 |
sCRP/mg/L | 0.890 (0.47, 2.55) | 2.050 (0.86, 6.19) | 0.023 |
Abbreviations: SD, standard deviation; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; SGRQ, St. George’s Respiratory Questionnaire; tHCY, total plasma homocysteine; sCRP, serum C-reactive protein; BMI, Body Mass Index.
Note: *Ethnicity was determined from the patient’s own perception.