Table 5.
Demographic, clinical data, vascular risk factors according to the tHcy levels
| Variables |
Low tHcy (≤ 12 μmol/L) (n = 59) |
High tHcy (>12 μmol/L) (n = 22) |
P-value |
|---|---|---|---|
| Age (years) | 55.5 ± 9.2 | 65.9 ± 10.3 | 0.005 |
| Males/females (n = 27/54) | 20/39 | 7/15 | 0.554 |
| Current smoking (n = 37) | 17 (45.9%) | 20 (54.1%) | 0.75 |
| Hypertension (n = 33) | 15 (45.5%) | 18 (54.5%) | 0.64 |
| Atrial fibrillation (n = 6) | 3 (50%) | 3 (50%) | 0.85 |
| Ischemic heart disease (n = 17) | 7 (41.1%) | 10 (58.8%) | 0.075 |
| Carotid stenosis (n = 21) | 5 (23.8%) | 16 (76.2%) | <0.0001 |
| Type of stroke | |||
| Infarction (n = 68) | 52 (76.5%) | 16 (20.5%) | 0.670 |
| Hemorrhage (n = 13) | 7 (53.8%) | 6 (46.2%) | 0.082 |
| Size of infarction | |||
| Large size of infarction (n = 10) | 3 (30%) | 7 (70%) | <0.0001 |
| Small size infarctions (n = 32) | 27 (84.4%) | 5 (15.6%) | <0.0001 |
| Lacunar infarctions (n = 26) | 16 (61.5%) | 10 (38.5%) | 0.001 |
| Post-stroke dementia (n = 17) | 6 (35.3%) | 11 (64.7%) | <0.0001 |
| P300 latency (delayed) | 311.05 ± 44.36 | 330.04 ± 45.50 | 0.008 |
| Depression (n = 20) | 12 (60%) | 8 (40%) | 0.075 |
Notes: Data are expressed as mean ± SD and number (%); significance between low and high homocysteine levels; significance is set at p-value < 0.05.