Table 4.
Change of metabolic and anthropometric parameters in depression responders and non-responders during milnacipran treatment
|
Responders n = 46 |
Non-responders n = 12 |
|||||
|---|---|---|---|---|---|---|
| baseline | 6 months | Δ | baseline | 6 months | Δ | |
| fBG | 153 | 111*** | –42 | 157 | 131 | –26 |
| HbA1c | 8.1 | 6.9*** | –1.2 | 7.7 | 7.1 | –0.6 |
| Bodyweight | 92.0 | 84.0* | –8.0 | 76.0 | 76.5 | +0.5 |
| BMI | 31.3 | 28.7* | –2.6 | 28.0 | 28.4 | +0.4 |
| Total cholest | 199.5 | 178.0*** | –21.5 | 198.5 | 182.0 | –16.5 |
| LDL | 119.0 | 109.0** | –10.0 | 110.5 | 95.0 | –15.5 |
| HDL | 47.0 | 47.0 | 0.0 | 47.0 | 49.0 | +2.0 |
| Triglyc | 196.0 | 159.0* | –37.0 | 151.0 | 146.0 | –5.0 |
Notes: All values are given as the median. Units are the same as those given in Table 2.
*
p > 0.05;
**
p > 0.01;
***
p > 0.001 for the difference between baseline and 6 months.
Abbreviations: fBG, fasting blood glucose; HbA1c, hemoglobin A1c; BMI, body mass index; Total cholest, total cholesterol; LDL, low density lipoprotein bound cholesterol; HDL, high density lipoprotein bound cholesterols; Triglyc, serum triglycerides.