Table 1.

List of the 22 SNPs on chromosome 2q31–q32 that have been included for global haplotype analysis

Order	SNPa	Allele	Chromosome position	Gene	Region	Distance between SNPs (BP)	Minor allele frequency		P valueb
							Depression	Control
1	rs1997207	C/G	178331945	PDE11A	Intron 19		0.06115	0.07886	0.2339
2	rs3770018	A/C	178366311	PDE11A	Intron 16	34,367	0.05755	0.112	0.000863
3	rs1465831	G/T	178394581	PDE11A	Intron 13	28,271	0.02698	0.04416	0.113
4	rs3770034	G/A	178426123	PDE11A	Intron 10	31,543	0.1367	0.1577	0.3077
5	rs1866212	A/G	178428793	PDE11A	Intron 10	2671	0.1787	0.1577	0.3342
6	rs1561320	T/C	178429529	PDE11A	Intron 10	737	0.1241	0.1562	0.1131
7	rs1866209	G/A	178432866	PDE11A	Intron 10	3,338	0.1241	0.1562	0.1131
8	rs1370656	A/C	178433505	PDE11A	Intron 10	640	0.06835	0.09621	0.08242
9	rs998059	G/T	178437777	PDE11A	Intron 10	4273	0.1241	0.1577	0.09731
10	rs1438048	C/A	178438353	PDE11A	Intron 10	577	0.1241	0.1562	0.1131
11	rs3770045	C/G	178454734	PDE11A	Intron 10	16,382	0.2428	0.2855	0.09622
12	rs1370661	G/A	178529090	PDE11A	Intron 6	74,357	0.2104	0.235	0.3098
13	rs2037757	G/A	178561572	PDE11A	Intron 5	32,483	0.3201	0.3785	0.03523
14	rs1405647	A/C	178584369	PDE11A	Intron 4	22,798	0.2176	0.235	0.4748
15	rs1880916	G/A	178620937	PDE11A	Intron 2	36,569	0.1151	0.142	0.1686
16	rs744397	T/C	178684625	PDE11A	Intron 2	63,689	0.1619	0.1845	0.3033
17	rs1432531	A/G	182833008	PDE1A	Intron 14	4,148,384	0.2518	0.2508	0.968
18	rs1991765	A/G	182864440	PDE1A	Intron 14	31,433	0.2284	0.224	0.855
19	rs1432534	G/T	182882952	PDE1A	Intron 11	18,513	0.2176	0.2271	0.6942
20	rs3769788	A/G	182884887	PDE1A	Intron 11	1936	0.2302	0.2256	0.8482
21	rs1432518	A/G	182923743	PDE1A	Intron 5	38,857	0.3489	0.3281	0.4481
22	rs1549870	A/G	182943110	PDE1A	Intron 3	19,368	0.05576	0.05047	0.6847

Notes: ^aThree SNPs, rs1866209, rs998059, and rs1438048, were first reported here. Other SNPs have been analyzed in previous published paper;¹²

^bThe p values correspond to the comparison of allele frequencies between the depression and control groups.

Abbreviations: BP, base pair; SNP, single-nucleotide polymorphisms; PDE, phosphodiesterase.