Table 3.
Effects of W. somnifera (L.) extracts on urine sugar, blood glucose, haemoglobin, glycosylated haemoglobin and liver glycogen.
| Groups | Urine Sugar | Blood glucose (mg/dL) | Hb (g/dL) | HbA1C (mg/gHb) | Liver glycogen (mg/g tissue) |
|---|---|---|---|---|---|
| Normal control | − | 92.17 ± 6.53 a | 15.25 ± 1.35 c | 1.84 ± 0.16 a | 28.21 ± 2.27 d |
| Diabetic control | +++ | 284.75 ± 15.86 d | 10.20 ± 0.90 a | 4.23 ±0.40 c | 16.51 ± 1.46 a |
| Diabetic + WSREt (100 mg/kg body weight) | + | 136.05 ± 4.92 c | 12.92 ± 1.14 bc | 2.05 ± 0.15 ab | 22.39 ± 1.09 b |
| Diabetic + WSREt (200 mg/kg body weight) | + | 100.12 ± 9.67 c | 14.60 ± 1.29 de | 1.90 ± 0.18 ab | 24.78 ± 2.19 c |
| Diabetic + WSLEt (100 mg/kg body weight) | + | 132.98 ± 6.52 c | 12.28 ± 0.64 b | 1.80 ± 0.09 a | 25.45 ± 1.85 c |
| Diabetic + WSLEt (200 mg/kg body weight) | + | 106.19 ± 4.71 b | 14.82 ± 1.35 de | 1.85 ± 0.18 a | 28.14 ± 2.16 d |
| Diabetic + glibenclamide | + | 110.77 ± 2.75 b | 13.76 ± 1.26 cd | 2.15 ± 0.20 b | 27.71 ± 1.45 d |
Values are expressed as mean ± SD of six samples from each group. Values with the same letter within columns are not significantly different using Duncan’s Multiple Range Test at 5% level (p ≤ 0.05). WSREt: W. somnifera root extract, WSLEt: W. somnifera leaf extract, haemoglobin (Hb), glycosylated haemoglobin (HbA1C).