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. 2009 Jun 26;5(6):e1000486. doi: 10.1371/journal.ppat.1000486

Table 1. Summary of Transporters Involved in Virulence or Toxin and Drug Efflux.

Transporter Family Name Fungus Description/Substrate Amino Acid Length References
ABC Transporters
PDR/ABCG CDR1 C. albicans Triazole resistance 1500 [60],[72]
PDR/ABCG CDR2 C. albicans Triazole resistance 1499 [71][73]
PDR/ABCG CgCDR1 C. glabrata Fluconazole, itraconazole 1542 [59]
PDR/ABCG CgCDR2/PDH1 C. glabrata Fluconazole, ketoconazole 1499 [61],[85]
PDR/ABCG CgSNQ2 C. glabrata Fluconazole, itraconazole 1507 [62]
PDR/ABCG AFR1 C. neoformans Triazole resistance 1543 [58]
PDR/ABCG ABC1 M. grisea Unknown function 1619 [46]
PDR/ABCG GpABC1 G. pulicaris Rishitin tolerance 1491 [51]
PDR/ABCG Mgatr4 M. graminicola Unknown function 1635 [49]
PDR/ABCG BcatrB B. cinerea Resveratrol tolerance 1439 [48],[50]
MRP/ABCC MLT1 C. albicans Unknown function, possibly bile 1606 [55]
MFS Transporters
DHA14 TOXA C. carbonum HC-toxin secretion 548 [34]
DHA14 TRI12 F. sporotrichioides Trichothecene T-2 secretion 598 [40]
DHA14 CFP C. kikuchii Cercosporin secretion 607 [35]
DHA12 CTB4 C. nicotianae Cercosporin secretion 512 [36]
DHA12 cefT A. chrysogenum Cephalosporin secretion 561 [42]
DHA14 PEP5 N. haematococca Unknown function 592 [52]
DHA12 MDR1 C. albicans Fluconazole resistance 564 [76][78]
DHA12 FLU1 C. albicans Fluconazole resistance 610 [79]
DHA12 CdMDR1 C. dubliniensis Fluconazole resistance 557 [80],[81]
DHA12 TMP1 C. albicans MDR 561 [83]
DHA12 TMP2 C. albicans MDR 581 [83]

Transporters involved in virulence are in bold.