Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Normal hematopoiesis. Long-term hematopoietic stem cells (LT-HSCs) maintain life-long hematopoiesis in the bone marrow (BM) via their ability to self-renew and to differentiate into all blood lineages. During differentiation, LT-HSCs transit through short-term (ST)–HSCs and committed progenitor stages (characterized by restricted lineage potential and reduced self-renewal capacity) before differentiating into mature myeloid, erythroid, or lymphoid lineages
