Table 3.

Direct and indirect costs. Derived from Lucioni et al (2005) and Dal Negro et al (2003b)

Costs (€/patient/year)
	Stage I	Stage II	Stage III	Stage IV
Direct cost independent of exacerbation	527.48	918.38	1592.59	3586.18
Direct cost per exacerbation		1219.46	1475.87	2637.33
Indirect cost independent of exacerbation		15.77	21.97	43.71
Indirect cost per exacerbation		27.81	38.76	77.10