TABLE III.
Reference | Phase | Treatment arms | Pts (n) | Median pfs(months) | Medianttp(months) | Medianos(months) | orr(%) |
---|---|---|---|---|---|---|---|
O’Shaughnessy et al., 200234 | iii | Docetaxel/capecitabine | 255 | nr | 6.1a | 14.5b | 42a |
Docetaxel | 256 | nr | 4.2 | 11.5 | 30 | ||
Albain et al., 200435 (abstract) | iii | Paclitaxel/gemcitabine | 267 | nr | 5.2b | 18.5b | 40.8 |
Paclitaxel | 262 | nr | 2.9 | 15.8 | 22.1 | ||
Beslija et al., 200638 (abstract) | ii | Docetaxel/capecitabine | 50 | nr | 9.3b | 22 | 68a |
Docetaxel to capecitabine at progression | 50 | nr | 7.7 | 19 | 40 |
p < 0.01.
p < 0.05.
Pts = patients; pfs = progression-free survival; ttp = time to progression; os = overall survival; orr = overall response rate; nr = not reported; 5-fu = 5-fluorouracil