TABLE II.
Marker | Region1 | Major > minor allele |
Minor allele frequency in | FBAT2 | |||
---|---|---|---|---|---|---|---|
Affected men (n = 542) |
Unaffected men (n = 473) |
N3 | Z-score | p-value | |||
rs13254738 | 2 | A>C | 0.34 | 0.35 | 191 | −0.29 | 0.78 |
rs6983561 | 2 | A>C | 0.08 | 0.06 | 49 | 2.21 | 0.03 |
rs6983267 | 3 | G>T | 0.41 | 0.43 | 189 | 2.07 | 0.04 |
rs7000448 | 3 | C>T | 0.41 | 0.40 | 187 | 0.72 | 0.47 |
DG8S737 | 1 | −84 | 0.08 | 0.07 | 62 | 0.71 | 0.48 |
rs10090154 | 1 | C>T | 0.13 | 0.13 | 106 | 0.06 | 0.95 |
Defined by Haiman et al.4
Under an additive model for the minor allele, except for rs6983267 (major allele).
Number of informative families.
Minor allele after collapsing alleles of DG8S737, i.e., −8 versus all others.