Table 5.
Characteristics | LVHs | HVHs | P value | ||
---|---|---|---|---|---|
No. of patients | % | No. of patients | % | ||
Age (years) | 0.24 | ||||
Median | 64 | 63 | |||
Range | 33–86 | 43–80 | |||
Gender | 0.53 | ||||
Male | 80 | 72.1 | 79 | 76.7 | |
Female | 31 | 27.9 | 24 | 23.3 | |
Comorbidity | 0.001a,* | ||||
No | 56 | 50.5 | 27 | 26.2 | |
1 organ system | 35 | 31.5 | 50 | 48.5 | |
2 organ systems | 18 | 16.2 | 23 | 22.3 | |
≥3 organ systems | 1 | 0.9 | 3 | 2.9 | |
Unknown | 1 | 0.9 | – | – | |
Histology | 0.98a,b | ||||
Adenocarc. | 73 | 65.8 | 71 | 68.9 | |
Squamous | 27 | 24.3 | 25 | 24.3 | |
Barrett’s dysplasia | 3 | 2.7 | 3 | 2.9 | |
Other | 2 | 1.8 | 3 | 2.9 | |
Unknown | 6 | 5.4 | 1 | 1.0 | |
Tumor localization | 0.61a,c | ||||
Cervical esoph. | 2 | 1.8 | 2 | 1.9 | |
Mid esoph. | 18 | 16.2 | 14 | 13.6 | |
Distal esoph./GE junction | 90 | 81.1 | 87 | 84.5 | |
Unknown | 1 | 0.9 | – | – | |
Stage (pTNM) | 0.90a | ||||
0 | 3 | 2.7 | 3 | 2.9 | |
I | 15 | 13.5 | 16 | 15.5 | |
II | 43 | 38.7 | 39 | 37.9 | |
III | 39 | 35.1 | 35 | 34.0 | |
IV | 6 | 5.4 | 9 | 8.7 | |
Unknown | 5 | 4.5 | 1 | 1.0 | |
Neoadjuvant treatment | 0.27a,d | ||||
No | 90 | 81.1 | 70 | 68.0 | |
Chemo ± radiotherapy | 21 | 18.9 | 33 | 32.0 | |
Surgical approach | <0.001a,e | ||||
Abdomino-cervical | 66 | 59.5 | 90 | 87.4 | |
Thoraco-abdominal | 10 | 9.0 | 1 | 1.0 | |
Abd-thor-cervical | 17 | 15.3 | 10 | 9.7 | |
Abdominal | 14 | 12.6 | 1 | 1.0 | |
Unknown | 4 | 3.6 | 1 | 1.0 | |
Anastomoses | <0.001f | ||||
Cervical | 86 | 77.5 | 101 | 98.1 | |
Thoracic | 12 | 10.8 | – | – | |
Abdominal | 13 | 11.7 | 2 | 1.9 | |
Total no. of patients | 111 | 103 |
LVHs low-volume hospitals (<10 resections/year), HVHs high-volume hospitals (≥10 resections/year), GE gastro-esophageal
a“Unknown” category excluded
bAdenocarcinoma/Barrett’s dysplasia versus squamous and others
cDistal esophagus/GE junction versus cervical/mid esophagus
dNo neoadjuvant therapy versus others
eAbdomino-cervical versus others
fCervical anastomoses versus others