Table 2.
Association of baseline characteristics with mortality in 170 cirrhotic patients, results from univariate Cox proportional hazards models
| Variables | P | Hazard ratio | 95% CI for Hazard ratio |
| Age (yr) | 0.68 | 0.56 | 0.36-1.06 |
| Sex (male) | 0.54 | 0.44 | 0.89-1.26 |
| Etiology (viral) | 0.66 | 0.58 | 0.40-1.11 |
| ALT (IU/L) (logn value) | 0.85 | 0.84 | 0.34-1.12 |
| AST (IU/L) (logn value) | 0.43 | 0.90 | 0.56-1.34 |
| ALT/AST ratio | 0.64 | 0.87 | 0.50-1.21 |
| Platelet count (× 109/L) (logn value) | 0.54 | 0.89 | 0.52-1.30 |
| Prothrombin time (s)1 (logn value) | 0.01 | 2.23 | 1.24-4.89 |
| INR for prothrombin time (logn value) | 0.03 | 1.99 | 1.13-3.96 |
| Partial thromboplastin time (s)2 (logn value) | 0.04 | 1.78 | 1.10-3.23 |
| Albumin (mg/dL) (logn value) | 0.001 | 3.12 | 1.89-5.23 |
| Bilirubin (mmol/L) (logn value) | < 0.001 | 3.89 | 2.12-6.14 |
| Creatinine (mmol/L) (logn value) | < 0.001 | 3.95 | 2.18-6.56 |
| Cholesterol (mmol/L) (loge value) | 0.03 | 1.83 | 1.34-3,42 |
| Ascites | < 0.001 | 4.05 | 2.27-6.33 |
| Spontaneous bacterial peritonitis | 0.001 | 3.05 | 2.10-5.07 |
| Encephalopathy | < 0.001 | 4.50 | 2.90-6.50 |
| Bleeding esophageal varices | < 0.001 | 4.78 | 3.11-7.11 |
CI: Confidence interval; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase. Hazard ratios (95% CI) for quantitative variables are expressed for 1 relevant unit increase of log. INR: International normalized ratio.
Prothrombin time (s): Value in seconds.
Partial thromboplastin time (s): Value in seconds.