Table 1.

Expression of IGF-(II) signaling axis constituents in human HCC

Signaling constituent	Dysregulation (%)
IGF-II	9.2[117]
	22.5[26]
	25.6-60[118]
	66.7[54]
	40[119]
	100[120]
	50[121]
	14[55]
IGF-IR	7-78[117]
	40[53]
IRS-1	46.7[53]
	100[122]
IRS-2	53.3[53]
	86[123]
IRS-4	46.7[53]