Table 1.
Univariate associations of baseline variables with death within 1 year, recurrent MI, and major bleed within 30 days
| Total | Death |
Recurrent MI |
Major bleed |
||||
|---|---|---|---|---|---|---|---|
| n (%) | P-value | n (%) | P-value | n (%) | P-value | ||
| Total | 13 819 | 524 (3.8) | — | 705 (5.1) | — | 645 (4.7) | — |
| Age (years) | |||||||
| Mean (SD) | 62.6 (11.7) | 70.8 (10.9) | <0.001 | 64.3 (11.3) | <0.001 | 67.6 (11.6) | <0.001 |
| White blood cell count (×1000/L) | |||||||
| Mean (SD) | 8.5 (3.0) | 9.9 (4.3) | <0.001 | 8.8 (3.4) | 0.016 | 9.2 (3.6) | <0.001 |
| Diabetes | |||||||
| None | 9857 | 301 (3.1) | 498 (5.1) | – | 418 (4.2) | – | |
| Non-ID diabetes | 2617 | 126 (4.8) | <0.001 | 130 (5.0) | 0.83 | 141 (5.4) | 0.013 |
| ID diabetes | 1193 | 92 (7.7) | <0.001 | 71 (6.0) | 0.19 | 79 (6.6) | <0.001 |
| ST-deviationa | 4825 | 270 (5.6) | <0.001 | 301 (6.2) | <0.001 | 290 (6.0) | <0.001 |
| Left bundle branch block | 423 | 46 (10.9) | <0.001 | 12 (2.8) | 0.037 | 33 (7.8) | 0.002 |
| Gender | |||||||
| Female | 4157 | 152 (3.7) | 199 (4.8) | — | 318 (7.6) | — | |
| Male | 9662 | 372 (3.9) | 0.60 | 506 (5.2) | 0.28 | 327 (3.4) | <0.001 |
| Planned treatment | |||||||
| Medical treatment | 4273 | 134 (3.1) | 40 (0.9) | — | 113 (2.6) | — | |
| PCI | 7754 | 245 (3.2) | 0.96 | 483 (6.2) | <0.001 | 460 (5.9) | <0.001 |
| CABG | 1647 | 124 (7.5) | <0.001 | 181 (11.0) | <0.001 | 64 (3.9) | 0.012 |
| Cerebrovascular event | 803 | 67 (8.3) | <0.001 | 54 (6.7) | 0.034 | 66 (8.2) | <0.001 |
| Creatinine clearance (mL/min) | |||||||
| Mean (SD) | 92 (42) | 72 (38) | <0.001 | 86 (36) | <0.001 | 77 (36) | <0.001 |
| Haemoglobin (g/dL) | |||||||
| Mean (SD) | 14.0 (1.6) | 13.4 (1.9) | <0.001 | 14.0 (1.7) | 0.57 | 13.3 (2.0) | <0.001 |
| Elevated CKMB/troponins | 7552 | 347 (4.6) | <0.001 | 464 (6.1) | <0.001 | 414 (5.5) | <0.001 |
| Current smoker | 3943 | 125 (3.2) | 0.028 | 203 (5.1) | 0.90 | 157 (4.0) | 0.017 |
| Previous MI | 4222 | 189 (4.5) | 0.001 | 239 (5.7) | 0.041 | 185 (4.4) | 0.24 |
| Treatment | |||||||
| Hep/Enox+GPIIb/IIIa | 4603 | 178 (3.9) | — | 228 (5.0) | — | 262 (5.7) | — |
| Bival+GPIIb/IIIa | 4604 | 176 (3.8) | 0.93 | 229 (5.0) | 0.93 | 243 (5.3) | 0.41 |
| Bival alone | 4612 | 170 (3.7) | 0.67 | 248 (5.4) | 0.34 | 140 (3.0) | <0.001 |
There were missing values for the following variables: white blood cells (n = 826), diabetic status (n = 152), ST-deviation (n = 15), left bundle branch block (n = 695), planned treatment (n = 145), cerebrovascular event (n = 192), creatinine clearance (n = 880), haemoglobin (n = 787), cardiac enzymes (n = 1107), smoking status (n = 262), and previous MI (n = 336). ID, insulin dependent.
aUsing definition from main ACUITY paper.