Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2009 Jun 14.

Published in final edited form as: Bone. 2007 Apr 27;41(2):247–255. doi: 10.1016/j.bone.2007.04.186

(A) Micro-computed tomography from three representative rat critical size femoral defects for each treatment group 8 weeks after surgery. The dotted box approximately indicates the original defect zone. (B) Morphometric analysis (bone volume per defect,[mm³]) of new bone formation from rat critical size femoral defects 8 weeks after surgery, and treated with pdHMSC grown for five weeks on rhBMP-2 loaded silk scaffolds (group I), rhBMP-2 loaded silk scaffolds seeded with udHMSC (group II), unseeded rhBMP-2 loaded silk scaffolds (group III), and untreated (control) defects (group IV). Error bars reflect 1 standard deviation. * Significantly (p<.05) greater than group IV data.

(A) Micro-computed tomography from three representative rat critical size femoral defects for each treatment group 8 weeks after surgery. The dotted box approximately indicates the original defect zone. (B) Morphometric analysis (bone volume per defect,[mm³]) of new bone formation from rat critical size femoral defects 8 weeks after surgery, and treated with pdHMSC grown for five weeks on rhBMP-2 loaded silk scaffolds (group I), rhBMP-2 loaded silk scaffolds seeded with udHMSC (group II), unseeded rhBMP-2 loaded silk scaffolds (group III), and untreated (control) defects (group IV). Error bars reflect 1 standard deviation. * Significantly (p<.05) greater than group IV data.