Table 2.
Microsatellite Markers for Known LCA Loci and Genes
| Marker | Max Heterozygosity | Type | Range (bp) |
|---|---|---|---|
| LCA3 Locus | |||
| D14S61 | 0.81 | Dinucleotide Repeat | 197-227 |
| D14S1022 | 0.73 | Dinucleotide Repeat | 236-246 |
| D14S68 | 0.91 | Dinucleotide Repeat | 148-172 |
| LCA9 Locus | |||
| D1S450 | 0.82 | Dinucleotide Repeat | 243-267 |
| D1S244 | 0.82 | Dinucleotide Repeat | 285-296 |
| D1S2667 | 0.83 | Dinucleotide Repeat | 224-272 |
| Marker | Gene | Type | Range (bp) |
|---|---|---|---|
| Known LCA Genes | |||
| D19S879L | CRX | Dinucleotide Repeat | 217-265 |
| GATA158H04L | AIPL1 | Tetrinucleotide Repeat | 174-194 |
| D1S1660L | CRB1 | Tetrinucleotide Repeat | 226-250 |
| D14S72L | RPGRIP1 | Dinucleotide Repeat | 257-271 |
| D14S1069L | RDH12 | Dinucleotide Repeat | 200-220 |
| D6S1645L | TULP1 | Tetrinucleotide Repeat | 226-252 |
| D17S1844L | GUCY2D | Dinucleotide Repeat | 227-249 |
| D4S3049L | LRAT | Dinucleotide Repeat | 210-236 |
| D12S1719L | CEP290 | Dinucleotide Repeat | 223-239 |
| D1S219L | RPE65 | Dinucleotide Repeat | 154-176 |
| D7S530L | IMPDH1 | Dinucleotide Repeat | 106-118 |
| D1S414L | RD3 | Dinucleotide Repeat | 185-205 |
| D1S425L | RD3 | Dinucleotide Repeat | 92-108 |
| D6S300L | LCA5 | Dinucleotide Repeat | 188-207 |
| D6S1619L | LCA5 | Dinucleotide Repeat | 189-211 |
| D6S286L | LCA5 | Dinucleotide Repeat | 206-232 |