. Author manuscript; available in PMC: 2009 Jun 14.

Published in final edited form as: Eur Neuropsychopharmacol. 2007 Jun 8;17(10):672–686. doi: 10.1016/j.euroneuro.2007.04.002

Table 1.

Group Statistics on Day one pre-injection

	grp	N	Mean	Std. Deviation	t	df	p

api1	PD	6	13.1667	13.80459	2.07	5.1	0.09
api1	NC	7	1.4286	1.81265	2.07	5.1	0.09

anx1	PD	6	3.1667	3.06050	1.24	5.57	0.26
anx1	NC	7	1.5714	.78680	1.24	5.57	0.26

borg1	PD	6	1.0833	1.20069	2.21	5.00	0.08
borg1	NC	7	.0000	.00000	2.21	5.00	0.08

Respiratory rate mean	PD	6	19.7833	1.83567	2.31	11	0.04
Respiratory rate mean	NC	7	16.9571	2.46093	2.31	11	0.04

Respiratory rate SD	PD	6	8.9000	2.69221	1.75	11	0.11
Respiratory rate SD	NC	7	5.4000	4.21782	1.75	11	0.11

Heart Rate mean	PD	6	75.6667	6.53197	2.92	11	0.01
Heart Rate mean	NC	7	63.4286	8.28366	2.92	11	0.01

Heart Rate SD	PD	6	6.3333	1.96638	0.56	11	0.59
Heart Rate SD	NC	7	5.5714	2.76026	0.56	11	0.59

Tidal Volume mean	PD	6	441.2667	103.67190	2.50	11	0.03
Tidal Volume mean	NC	7	302.6714	96.32365	2.50	11	0.03

Tidal Volume SD	PD	6	249.5050	58.18643	3.27	11	0.008
Tidal Volume SD	NC	7	115.3571	84.71861	3.27	11	0.008

Minute Ventilation mean	PD	6	8.1200	1.77871	3.91	11	0.002
Minute Ventilation mean	NC	7	4.9300	1.14158	3.91	11	0.002

Minute Ventilation SD	PD	6	5.8550	2.98554	2.40	11	0.04
Minute Ventilation SD	NC	7	2.5086	2.03266	2.40	11	0.04

These are values on day 1, before saline injection. For the physiological measures these are 5 minute means before injection. For the scales these are the −10 minute measures.

API and Borg show a trend toward significance between the two groups. However the respiratory variables and heart rate are significantly higher in the PD groups prior to injection. With significantly greater variance (standard deviations) for tidal volume and minute ventilations in the PD group. You can argue that this difference is caused by the greater anticipatory anxiety in the patients, to receiving the injection (which the patients believe can be doxapram and cause a panic attack).