Skip to main content
. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: Neurobiol Dis. 2008 Jan 5;30(1):130–138. doi: 10.1016/j.nbd.2007.12.009

Fig. 2.

Fig. 2

A comparison of 8-OHdG generation in the mitochondrial and nuclear genomes following SE. Hippocampal tissue was harvested at the indicated time points, DNA extracted and HPLC performed as described in Materials and Methods. DNA damage was expressed as the ratio of oxidized DNA base (8-OHdG) to non-oxidized base (2-dG) in mtDNA and nDNA. Bars represent mean ± SEM. *P<0.05 mtDNA vs. saline treated controls, #P<0.05 mtDNA vs. nDNA, one way ANOVA, n= 6 per group.

HHS Vulnerability Disclosure