Figure 6. In vivo treatment with glial growth factor 2 and basic fibroblast growth factor spinal cord injury results in increased numbers of EGFP⁺CC1⁺ oligodendrocytes.

SCI Mice were injected subcutaneously with 0.02mg/kg FGF2 and 0.8mg/kg GGF2 for 8 days, beginning at 1 DPI, and sacrificed on day 9. NG2 immunoreactivity was increased in GGF2 + FGF2 mice (A), compared to saline-injected controls (B). EGFP⁺CC1⁺ oligodendrocytes were also increased in GGF2 + FGF2 treated mice (C). D. Quantification of NG2⁺ cells indicating a significant increase in EGFP^negNG2⁺ cells. E. Quantification of CC1⁺ cells indicating a significant increase in EGFP⁺CC1⁺ oligodendrocytes; bars represent mean ± SEM. Two-way ANOVA was performed with Bonferrroni’s post-hoc analysis.