Table 1.
Dose-dependent blocking of [18F]FEOBV in mouse brain striatum and cortex using unlabeled FEOBV co-administration. STR/CBL and CTX/CBL are striatum- and cortex-to-cerebellum ratios determined by dissection at three hours after radiotracer injection.
FEOBV dose | STR/CBL | CTX/CBL |
---|---|---|
0 (control) | 4.95 +/- 0.93 | 2.76 +/- 0.89 |
2 μg/kg | 4.53 +/- 0.49 | 2.70 +/- 0.28 |
5 μg/kg | 4.35 +/- 0.59 | 2.72 +/- 0.31 |
10 μg/kg | 3.58 +/- 0.14 | 2.14 +/- 0.15 |