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. 2009 Jun 22;4(6):e5995. doi: 10.1371/journal.pone.0005995

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Kang, Vaucher.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Effects of scopolamine (B, Sco+CCh), CPP (C, CPP+CCh), mecamylamine (D, Mec+CCh) or MLA (E, MLA+CCh) infusion prior to CCh administration are shown compared to aCSF+CCh injected animals as control group (black histograms). The long term enhancement of VEP amplitude is abolished in an identical manner by scopolamine, CPP and mecamylamine, suggesting that mAChR and nAChR could act upstream of NMDAR intracellular pathways. Drug infusion time points are indicated by black arrows.