Table 2. Latency of VEP after CCh injection or HDB stimulation and drug treatment.
Latency (ms) | 0 min | 30 min | 60 min | 90 min | 120 min | 150 min | 180 min | 210 min |
Cholinergic enhancement | ||||||||
Control | 36±3 | 35±3 | 37±3 | 35±4 | 35±2 | 33±4 | 34±3 | 35±4 |
Carbachol (CCh) | 37±3 | 37±2 | 36±4 | 34±3 | 29±3 | 26±5 | 31±3 | 31±3 |
HDB stimulation | 35±4 | 32±2 | 33±3 | 33±3 | 35±3 | 33±4 | 36±1 | 35±3 |
Sco (i.p.)+CCh | 37±1 | 41±1 | 40±2 | 40±2 | 35±4 | 38±3 | 39±5 | 37±2 |
CCh+Sco (i.p.) | 38±1 | 38±3 | 35±1 | 33±1 | 33±1 | 35±5 | 33±3 | 36±1 |
Pharmacological treatment | ||||||||
aCSF+CCh | 38±2 | 37±4 | 35±4 | 33±3 | 36±3 | 32±3 | 32±3 | 35±2 |
Sco(i.c.)+CCh | 38±5 | 37±2 | 41±1 | 39±3 | 43±5 | 40±6 | 44±5 | 39±6 |
Mec+CCh | 39±1 | 38±3 | 38±2 | 37±6 | 46±3 | 45±4 | 30±4 | 38±4 |
MLA+CCh | 40±2 | 41±4 | 39±2 | 37±4 | 36±4 | 37±3 | 39±3 | 37±2 |
CPP+CCh | 39±3 | 36±4 | 36±2 | 34±3 | 38±2 | 38±5 | 31±4 | 30±6 |
Values are expressed in mean±SD of ms after the stimulation artefact. There was no effect of the treatment on latency.