. Author manuscript; available in PMC: 2009 Jul 28.

Published in final edited form as: Nature. 2008 Dec 10;457(7229):599–602. doi: 10.1038/nature07586

Table 1.

Frequency of GNAQ mutations in melanocytic neoplasms The number and type of samples analyzed is shown.

	Diagnosis	% Mutant	N
Cutaneous and mucosal melanomas	Melanoma on skin without chronic sun-induced damage (non- CSD)²²	0%	15
	Melanoma on skin with chronic sun-induced damage (CSD)²²	4%	27
	Acral melanoma	0%	15
	Mucosal melanoma	0%	14
	“Malignant blue nevus”	50%	2
	Melanoma arising in congenital nevus	0%	3
	Spitzoid melanoma	0%	2
	Total		78
Nevi	Blue nevus	83%	29
	Nevus of Ota	6%	17
	Congenital nevus	0%	7
	Deep penetrating nevus	0%	16
	Proliferating nodule in giant congenital nevus	0%	7
	Spitz nevus	0%	8
	Total		84
Ocular melanomas	Uveal melanoma	46%	48
	Uveal melanoma cell line	27%	15
	Conjunctival melanoma	0%	11
	Total		74
	Grand Total		236