Table 2.
Male-predominant liver genes in wt mice
| Gene | Accession Number |
Expression Ratio (average) |
|||
|---|---|---|---|---|---|
| M-wt/F-wt | M-rsl/M-wt | M-R1/M-rsl | M-R2/M-rsl | ||
| Ddx3y | AA210261 | 130.62 | 1.05 | 0.85 | 0.93 |
| Moxd1 | NM_021509 | 52.73 | 1.12 | 2.30 | 2.60 |
| Eif2 s3y | NM_012011 | 41.25 | 1.03 | 1.06 | 1.03 |
| >Elovl3* | BC016468 | 33.51 | 0.30 | 1.83 | 2.37 |
| Cyp4a12 | BC025936 | 22.82 | 1.19 | 0.82 | 0.80 |
| >Asns* | AV212753 | 14.41 | 0.40 | 3.01 | 2.88 |
| >Ugt2b38 | AI118428 | 12.66 | 2.15 | 0.69 | 0.81 |
| Jarid1d | AF127244 | 12.25 | 0.67 | 1.24 | 1.34 |
| >Hsd3b5* | NM_008295 | 10.33 | 1.00 | 0.99 | 1.02 |
| E130013N09Rik | BI731047 | 9.77 | 0.40 | 1.24 | 1.02 |
| >Cml4 | NM_023455 | 9.29 | 0.61 | 1.14 | 1.04 |
| Olig1 | AB038696 | 7.99 | 0.45 | 0.67 | 0.71 |
| >Serpine2 | NM_009255 | 7.51 | 0.55 | 0.94 | 0.69 |
| Serpina12 | AK014346 | 7.25 | 0.97 | 1.19 | 1.15 |
| Uty | BB207470 | 7.12 | 0.94 | 0.92 | 1.02 |
| Gnai1 | BQ174580 | 7.00 | 0.50 | 0.82 | 0.69 |
| 9330164H19Rik | BB768758 | 5.85 | 0.77 | 0.80 | 1.59 |
| C6 | NM_016704 | 5.63 | 1.26 | 0.99 | 1.01 |
| Keg1 | AI746421 | 5.50 | 0.47 | 1.36 | 0.94 |
| Cml5 | BC024605 | 5.26 | 0.62 | 1.33 | 1.15 |
Shown are the top 20 male-predominant genes in wt mice. In bold are genes that also appear to be Rsl-regulated due to their differential expression in rsl and Rsl1 (R1) and Rsl2 (R2) transgenic mice. >, Male-predominant genes regulated by Rsl.
*
Expression patterns have been validated by Q-RT-PCR. Hsd3b5 is male-predominant, however, by microarray, appeared Rsl-regulated only in females.