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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Virology. 2009 Jan 9;385(1):126–133. doi: 10.1016/j.virol.2008.11.039

Figure 1. Extracellular IL-12p40 and IL-10 expression by DC.

Figure 1

To analyze extracellular IL-12p40 and IL-10 production, culture supernatants from Tg and control rats (n=6) were assayed by capture ELISA. BMDC were stimulated with LPS and media was collected and analyzed in duplicate. (Panel A), expression of IL-12 by Tg BMDC was 1089 ± 807 pg/ml and 1226 ± 883 at 24 hr and 48 hr. stimulation compared with 4789 ± 2231 pg/ml and 5825 ± 3320 by age-matched controls at the same time points. (Panel B), IL-10 expression by Tg BMDC was 73 ± 61 pg/ml (n=6) pg/ml after 24 compared with 13 ± 11 for age matched controls. * Indicates a significant difference by Mann-Whitney test for samples exhibiting non-normal distribution.