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. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: Neurosci Lett. 2006 Dec 18;412(3):233–238. doi: 10.1016/j.neulet.2006.11.016

Figure 4.

Figure 4

Cdk5 is required for primary sensory neurogenesis. Immunostaining of 24 hpf embryos with an antibody against islet-1 marks (lateral views of the anterior regions of the embryos) primary neurons in (A) control siRNA-injected, (B) cdk5 siRNA-injected, and (C) cdk5 siRNA with cdk5 mRNA (200 pg)-injected embryos. Arrowheads indicate some of the neurons. (D) Quantitative analyses of islet-1 positive neurons are presented. Acetylated α-tubulin (acetyl α-tub) staining reveals the primary sensory neurons in the trigeminal ganglia of the zebrafish (lateral views) injected with control siRNA (E), cdk5 siRNA (F) and cdk5 siRNA plus cdk5 mRNA (G).