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. 2009 Jun 30;6(6):e1000104. doi: 10.1371/journal.pmed.1000104

Figure 3. Pharmacokinetics of oxime administration.

Figure 3

Red cell acetylcholinesterase activity (mean±SD) in patients poisoned by diethyl (blue) and dimethyl (red) OP insecticides, with (solid) and without (broken) pralidoxime chloride. Normal acetylcholinesterase activity is 600–700 mU/µmol Hb; an activity greater than 20%–30% of normal allows normal NMJ function [32]. Acetylcholinesterase was effectively reactivated after poisoning with diethyl insecticides but less so after dimethyl insecticide poisoning.