Table 2. Baseline analytical laboratory characteristics.
Baseline Characteristics | Subcategory | Placebo (n = 114) | Pralidoxime (n = 121) |
OP insecticide class at randomisation, n (%) | Dimethyl | 47 (41.2) | 46 (38.3) |
Diethyl | 49 (43.0) | 54 (45.0) | |
Unknown | 18 (15.8) | 20 (16.7) | |
OP insecticide class after lab analysis, n (%) | Number | 112 | 121 |
Dimethyl | 33 (29.5) | 39 (32.2) | |
Diethyl | 50 (44.6) | 62 (51.2) | |
S-alkyl | 2 (1.8) | 0 | |
Mixed | 2 (1.8) | 1 (0.8) | |
Unknown | 21 (18.8) | 16 (13.2) | |
No OP detected | 4 (3.6) | 3 (2.5) | |
BuChE activity on admission, mU/ml | Number | 103 | 106 |
Median (IQR) | 110 (9 to 746) | 86 (6 to 920) | |
Dimethyl, median (IQR) (n) | 431 (20 to 1606) (n = 41) | 733 (73 to 1876) (n = 39) | |
Diethyl, median (IQR) (n) | 15 (0 to 144) (n = 46) | 10 (0 to 99) (n = 49) | |
Other or unknown, median (IQR) (n) | 122 (34 to 818) (n = 16) | 121 (10 to 740) (n = 17) | |
Red cell AChE activity before treatment, mU/µmol Hb | Number | 92 | 102 |
Median (IQR) | 28 (7 to 59) | 44 (12 to 97) | |
Dimethyl, median (IQR) (n) | 9 (2 to 32) (n = 36) | 17 (6 to 70) (n = 37) | |
Diethyl, median (IQR) (n) | 47 (27 to 65) (n = 40) | 60 (34 to 116) (n = 47) | |
Other or unknown, median (IQR) (n) | 20 (6 to 115) (n = 16) | 33 (4 to 68) (n = 17) | |
Aged red cell AChE before Rx, % | Number | 92 | 101 |
Median (IQR) | 59 (34 to 96) | 46 (29 to 89) | |
Dimethyl, median (IQR) (n) | 97 (61 to 100) (n = 36) | 89 (56 to 99) (n = 36) | |
Diethyl, median (IQR) (n) | 34 (20 to 45) (n = 40) | 35 (21 to 45) (n = 48) | |
Other or unknown, median (IQR) (n) | 84 (47 to 92) (n = 16) | 72 (34 to 100) (n = 16) |
Data were collected on admission to hospital; recruitment occurred soon after.
Abbreviations: AChE, acetylcholinesterase; BuChE, butyrylcholinesterase.