Fig. 3.

RNAi machinery: Leishmania braziliensis versus Trypanosoma brucei. Schematic representation of the main components of the RNAi pathways identified by sequence similarity and/or functional evaluation in T. brucei (Tb) and L. braziliensis (Lb). Comparisons of the gene products and their domains in each species are accompanied by their GeneDB gene IDs; Tb927, T. brucei genes; LbrM, L. braziliensis genes. Domain IDs are depicted on the left. RGG indicates a domain containing arginine-glycine-glycine repeats; SNase indicates the Staphylococcal nuclease domain present in TudorSN proteins. ^∗Indicates genes confirmed to be functionally active in the T. brucei RNAi pathway.