Table 2.
Genome facts: the Leishmanias versus Trypanosoma brucei
| Leishmania major | Leishmania infantum | Leishmania braziliensis | Trypanosoma brucei | |
|---|---|---|---|---|
| Total size (Mb) | 32.8 | 32.1 | 32.0 | 26.1 |
| Contigs | 36 | 562 | 1,041 | 30 |
| No. of chromosomes | 36 | 36 | 35 | 11∗ |
| Chromosome size range (Mb) | 0.3–2.8 | 0.3–2.8 | 0.3–2.8 | 1–5.2 |
| Overall G + C content % | 59.7 | 59.3 | 60.4 | 46.4 |
| No. of genes | 8,298 | 8,154 | 8,153 | 9,068 |
| No. of pseudogenes | 97 | 41 | 161 | 904 |
| Average gene size (bp) | 1,894 | 1,868 | 1,873 | 1,592 |
| Gene density (per Mb) | 252 | 235 | 258 | 317 |
| Coding percentage | 48.0 | 44.0 | 48.5 | 50.5 |
| Coding G + C content % | 62.5 | 62.4 | 60.4 | 50.9 |
| No. of DGCs | 133 | 133 | n/a | 127 |
| Average DGC length (kb/genes) | 240/61 | n/a | n/a | 204/71 |
| No. of tRNAs | 83 | 62 | 66 | 65 |
| No. of snoRNAs | 693 | n/a | n/a | 353 |
| No. of snRNAs | 6 | n/a | n/a | 5 |
| No. of rRNAs | 63 | n/a | n/a | 56 |
| Average intergenic size | 1,939 | 2,049 | 1,976 | 1,279 |
| Active mobile elements | None (degenerate RIME/DIRE) | None (degenerate RIME/DIRE) | TATEs, SLACS | ingi, RIME, DIRE, SLACs, SIRE, VIPER |
Data included in this Table are correct as of February 2007 (for Leishmania species) and July 2005 (for T. brucei). *, only the megabase chromosome are included, not the intermediate or mini-chromosomes. DGC, directional gene cluster; RIME, ribosomal mobile element; DIRE, degenerate ingi/L1Tc-related element; TATE, telomere-associated transposable element; SLACS, Spliced Leader Associated Conserved Sequence; SIRE, short interspersed repetitive element; VIPER, LTR retroelement related to SIRE.