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. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: J Immunol. 2006 Jul 15;177(2):925–933. doi: 10.4049/jimmunol.177.2.925

Figure 2.

Figure 2

The ability to activate naïve T cells specific for an alternative antigen rapidly diminishes following infection. BALB/c recipient mice (Thy1.2+) were infected with transgenic Leishmania promastigotes expressing ovalbumin (Leishmania-OVA) and CFSE-labeled DO11.10 transgenic T cells were transferred at the indicated times following infection. Three days following transfer, cells were harvested and analyzed by flow cytometry. Histogram plots were gated on donor cells (KJ126+CD4+). The number in the corner represents the percentage of donor cells that were CFSEdim in the non-draining or dLNs.