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. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: J Immunol. 2006 Jul 15;177(2):925–933. doi: 10.4049/jimmunol.177.2.925

Figure 4.

Figure 4

Antigen presentation to an unrelated antigen is intact at seven days following L. major infection. BALB/c recipient mice (Thy1.2+) were infected with L. major. Six days following infection one group of mice was injected with 25ug of OVA protein in the same footpad (d6-OVA/d7-Leish). As controls, mice were given protein alone (d1-OVA), infected with L. major for one or seven days (d1-Leish and d7-Leish, respectively), or infected and immunized at the same time (d1-Leish/OVA). CFSE-labeled OVA-specific (DO11.10) transgenic T and ABLE Thy1.1+ cells were adoptively transferred into the recipient mice at the indicated time points. The dLNs were harvested and analyzed by flow cytometry three days following transfer. Histogram plots were gated on KJ1-26+CD4+ (DO11.10) or Thy1.1+ (ABLE) donor cells in the dLNs of recipient mice. The data are representative of three experiments.