Table 1.
Demographic Characteristics of Alzheimer’s Disease Neuroimaging Initiative Study Subjects Who Provided a Cerebrospinal Fluid Sample at the Baseline Visit
| Characteristics | AD | MCI | NC |
|---|---|---|---|
| n | 100 | 196 | 114 |
| Sex, M/F | 58/42 (58%) | 131/65 (67%) | 58/56 (51%) |
| Age, yr | |||
| Median | 76 | 75 | 76 |
| Mean ± SD | 75 ± 8 | 75 ± 7 | 76 ± 5 |
| 95% CI | 73–77 | 74–76 | 75–77 |
| MMSE score | |||
| Median | 24 | 27 | 29 |
| Mean ± SD | 23.5 ± 1.9 | 26.9 ± 1.8 | 29.1 ± 1.0 |
| 95% CI | 23.2–23.9 | 26.7–27.2 | 28.9–29.3 |
| ADAS Cog 11 | |||
| Median | 17.2 | 11.3 | 6.3 |
| Mean ± SD | 18.2 ± 6.2 | 11.6 ± 4.5 | 6.4 ± 2.9 |
| 95% CI | 16.9–19.4 | 11–12.3 | 5.9–6.9 |
| ApoE ε4+/ε4− | 69/31 (69%) | 106/90 (54%) | 27/87 (24%) |
AD = Alzheimer’s disease; MCI = mild cognitive impairment; NC = cognitively normal; SD = standard deviation; CI = confidence interval; MMSE = Mini-Mental State Examination; ApoE = apolipoprotein; ADAS Cog 11 = Alzheimers Disease Assessment Scale-cognitive subscale 11.