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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Biochim Biophys Acta. 2008 Nov 27;1794(5):808–816. doi: 10.1016/j.bbapap.2008.11.005

Figure 3.

Figure 3

Docking of an ampicillin molecule at the constriction zone of an OmpF monomer. The top panel shows the fit of the ampicillin molecule within the pore, with the carboxylate group attracted to the cluster of arginines in the OmpF barrel, and the ammonium group close to the acidic L3 loop residues. Colors of atoms in ampicillin are as follows: green for carbon, red for oxygen, blue for nitrogen and yellow for sulfur. Hydrogen atoms are not shown. The OmpF backbone is shown as a yellow ribbon. The lower panel shows the solvent accessible surface of the OmpF eyelet highlighting the electrostatic potential with blue color for positive potential and red color for negative potentials. Ampicillin is shown in a stick model with the following colors: white for carbon, red for oxygen, blue for nitrogen, green for sulfur and violet for hydrogen. Reproduced from reference 70 with permission (copyright © 1993–2008 by The National Academy of Sciences of the United States of America, all rights reserved).