Table 3.

Proportions of Subjects Meeting MacCAT-CR and UBACC Capability Criteria With the 2 Consent Conditions

	Routine Consent, % Capable (N = 29)	Multimedia Consent, % Capable (N = 31)	Relative “Risk” of Capabilitya	95% Confidence Interval	Fisher Exact Test/P Value
Healthy Comparison Subjects
CATIE criterion
Trial 1	100	100	1.000	N/A	N/A
Trial 2	100	100	1.000	N/A	N/A
Trial 3	100	100	1.000	N/A	N/A
UBACC criterion	86	94	1.085	0.94, 1.32	0.417
Capacity determination by psychiatrist based on MacCAT-CRb
Trial 1	90	100	1.115		0.107
Trial 3	97	100	1.036		0.483
Schizophrenia patients
CATIE criterion
Trial 1	59	81	1.365	1.09, 1.75	0.012
Trial 2	77	92	1.190	1.03, 1.40	0.028
Trial 3	77	94	1.211	1.05, 1.42	0.012
UBACC criterion	47	76	1.614	1.22, 2.22	0.001
Capacity determination by psychiatrist based on MacCAT-CRb
Trial 1	47	66	1.408	1.04, 1.97	0.034
Trial 3	70	89	1.273	1.06, 1.55	0.010

Note: MacCAT-CR, MacArthur Competence Assessment Tool for Clinical Research; UBACC, University of California, San Diego Brief Assessment of Capacity to Consent; CATIE, Clinical Antipsychotic Trials of Intervention Effetiveness; N/A, not applicable. Values in bold are the P values for those Fisher Exact tests that were statistically significant.

^aRelative “risk” = P (capable|multimedia)/P (capable|routine).

^bClinical determination of capacity by an independent psychiatrist based on MacCAT-CR responses.