Table 2.
Characteristics of studied groups
| p | |||||
| CT2DM | LOADDM | N | N vs CT2DM | N vs LOADDM | |
| n | 48 | 18 | 42 | NS | NS |
| age (years) | 65.6 ± 7.1 | 67.4 ± 10.8 | 63.0 ± 11.2 | NS | NS |
| age at diagnosis (years) | 54.9 ± 8.4 | 54.7 ± 10.0 | - | - | - |
| weight (kg) | 73.2 ± 13.7 | 73.4 ± 15.3 | 61.4 ± 13.4 | <0.01 | <0.05 |
| BMI (kg/m2) | 28.7 ± 4.2 | 28.5 ± 4.3 | 25.3 ± 3.7 | <0.01 | <0.05 |
| waist (cm) | 98.7 ± 10.7 | 99.4 ± 13.0 | 86.3 ± 9.9 | <0.01 | <0.01 |
| Systolic BP (mmHg) | 125.3 ± 16.0 | 118.0 ± 13.6 | 130.1 ± 17.3 | NS | <0.05 |
| Diastolic BP (mmHg) | 75.2 ± 7.6 | 72.6 ± 8.7 | 81.8 ± 9.0 | <0.01 | <0.01 |
| FBG (mmol/l) | 7.18 ± 1.69 | 6.41 ± 1.91 | 4.98 ± 0.33 | <0.01 | <0.01 |
| A1c (%) | 6.4 ± 2.4 | 7.4 ± 1.2 | 5.5 ± 0.6 | 0.07 | <0.01 |
| total cholesterol (mmol/l) | 4.44 ± 0.87 | 4.56 ± 0.97 | 4.94 ± 1.04 | <0.05 | NS |
| HDL-cholesterol (mmol/l) | 1.23 ± 0.35 | 1.18 ± 0.28 | 1.43 ± 0.43 | <0.05 | 0.07 |
| LDL-cholesterol (mmol/l) | 2.35 ± 0.64 | 2.64 ± 0.86 | 2.96 ± 0.84 | <0.01 | NS |
| triglycerides (mmol/l) | 1.45 (1.07–2.07) | 1.36 (1.05–1.84) | 1.14 (0.78–1.48) | <0.05 | NS |
| HOMA-%B1 | 77.1 ± 42.7 | 80.5 ± 46.1 | 107.8 ± 40.0 | <0.01 | NS |
| HOMA-IR1 | 2.12 ± 1.28 | 2.43 ± 1.39 | 1.27 ± 0.64 | <0.05 | NS |
| fasting C-peptide (nmol/l) | 0.78 ± 0.50 | 0.77 ± 0.56 | 0.57 ± 0.29 | NS | NS |
| p2 | |||||
| females (%) | 68.8 | 72.2 | 83.3 | NS | |
| hypertension (%) | 85.4 | 72.2 | 50 | <0.01 | |
| obesity (%) | 31.3 | 22.2 | 11.9 | NS | |
| overweight (%) | 83.3 | 66.7 | 52.4 | <0.01 | |
| central obesity (%) | 62.5 | 61.1 | 38.1 | 0.051 | |
| low HDL (%) | 63.8 | 50 | 34.1 | <0.05 | |
| hypertriglyceridemia (%) | 38.8 | 33.3 | 17.7 | NS | |
| dyslipidemia treatment (%)3 | 8.3 | 0 | 7.1 | NS | |
| metabolic syndrome (%) | 87.5 | 77.8 | 11.9 | <0.01 | |
| insulin treatment (%)4 | 14.9 | 37.5 | - | 0.054 | |
| positive GADA (%) | 4.9 | 0 | 2.6 | NS | |
1calculated in 39 individuals from group CT2DM, 14 from LOADDM, and 39 from N; 2Two df significance, except 4(one df); 3current or previous use of fibrates/statins; NS denotes p< 0.10