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. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: Am J Obstet Gynecol. 2008 Apr;198(4):474.e1–474.11. doi: 10.1016/j.ajog.2007.11.057

Figure 2. Structural changes associated with uterine leiomyoma.

Figure 2

Figure 2

2A–D: FITC-Phalloidin staining of sections from matched leiomyoma and myometrial samples. Staining for actin in fibroid samples reveals a disordered structure and is markedly different from normal myometrium. Leiomyoma (A) and myometrium (B) were from the same uterus; leiomyoma (C) and myometrium (D) were from a separate specimen. Note the deformed nuclei and cell structure in A and C. Representative studies. Magnification 40X.

2 E,F: Staining of paired leiomyoma (E) and myometrium (F) for RhoA (1:1000) suggested increased staining. Magnification=40X.

2 G,H: Staining of paired leiomyoma (G) and myometrial (H) sections for alpha-smooth muscle actin (1:1500). Expression was slightly increased in leiomyoma cells. Magnification=40x