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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Exp Neurol. 2009 May 3;218(1):129–136. doi: 10.1016/j.expneurol.2009.04.018

Figure 4. Acute sleep deprivation antagonizes LPS induced cytokine expression in the CNS.

Figure 4

RT-PCR analysis of forebrain homogenates 4 hours after lipopolysaccharide (LPS; 400μg/kg) or vehicle treatment administration A) interleukin-1β (IL-1β), B) tumor necrosis factor alpha (TNFα), C) interleukin-6 (I-6) and D) interleukin 10 (IL-10). All gene expression data are presented after relativization to 18s rRNA expression. Differences were considered significant if p<0.05. ASD, acute sleep deprivation. All data are presented as means (± SEM). N=5–6/group.