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Effect of complement blocking on E-selectin expression on immortalized Gal+/+ and Gal−/− PAECs. Gal+/+ (●) and Gal−/− (○) PAECs were incubated with human whole blood and increasing concentrations of the complement-inhibitors compstatin (left panel) and a C5aR antagonist (middle panel) as well as a control peptide (right panel). E-selectin expression on incubated PAEC was determined by flow cytometry. Representative data from one blood donor are presented.
