Figure 4.
Photoaffinity labeling of DAT with [125I]-6. Cells expressing rDAT or 6X-his- hDAT were photoaffinity-labeled with [125I]-6 in the absence or presence of 100 μM (−)-cocaine. Cells were solubilized and DATs were immunoprecipitated with DAT antibody 16 (rDAT) or anti-his antibody (hDAT) followed by SDS-PAGE and autoradiography.