Table 3. Positive and negative predictive values of functional in vitro tests.
Test system | Released LT (17, 18, e7) | CD63 (6, 18, 19, e9) | FET (6, 14, 21, 22, e18, e19, e22) | ||||||
Parameter | PPV | NPV | (n) | PPV | NPV | (n) | PPV | NPV | (n) |
Skin/respiratory tract | 96 | 78 | (88) | 95 | 56 | (90) | 90 | 93 | (465 |
Respiratory tract | 92 | 82 | (66) | 86 | 78 | (50) | 89 | 92 | (407) |
Skin | 93 | 94 | (72) | 93 | 67 | (70) | 96 | 97 | (58) |
Stomach | – | – | – | – | – | – | 70 | 98 | (102) |
Intestine | – | – | – | – | – | – | 87 | 69 | (132) |
Respiratory tract/skin/intestine/stomach | – | – | – | – | – | – | 87 | 87 | (699) |
PPV, positive predictive value in %; NPV, negative predictive value in %; n, size of the test group; LT, leukotrienes; CD, cluster of differentiation; FET, functional eicosanoid test