Table 2. Marker distribution in 122 paired tumour (1) and normal tissues (0) and the distribution of the expression ratios of tumour to normal.
| Marker | CA/normal | Median (1st, 3rd quartile) | Mean ratioa (s.e.) | 95% CI | P-value** |
|---|---|---|---|---|---|
| KLK5 | 1 | 0.005 (0.004, 0.008) | 0.985 (0.146) | 0.736–1.318 | 0.9198 |
| 0 | 0.006 (0.005, 0.01) | . | |||
| KLK6 | 1 | 0.4485 (0.104, 1.684) | 15.548 (2.47) | 11.388–21.228 | <0.0001 |
| 0 | 0.0315 (0.01, 0.06) | . | |||
| KLK7 | 1 | 0.29 (0.171, 0.51) | 2.323 (0.235) | 1.905–2.832 | <0.0001 |
| 0 | 0.13 (0.078, 0.217) | . | |||
| KLK8 | 1 | 0.009 (0.005, 0.023) | 2.001 (0.221) | 1.611–2.485 | <0.0001 |
| 0 | 0.0055 (0.004, 0.008) | . | |||
| KLK10 | 1 | 0.464 (0.071, 2.206) | 33.307 (6.398) | 22.857–48.535 | <0.0001 |
| 0 | 0.008 (0.005, 0.029) | . | |||
| KLK11 | 1 | 0.817 (0.291, 1.98) | 3.131 (0.435) | 2.385–4.11 | <0.0001 |
| 0 | 0.266 (0.15, 0.568) | . | |||
| KLK13 | 1 | 0.009 (0.005, 0.016) | 1.518 (0.148) | 1.254–1.838 | <0.0001 |
| 0 | 0.005 (0.004, 0.008) | . | |||
| KLK14 | 1 | 0.035 (0.019, 0.061) | 0.98 (0.123) | 0.767–1.253 | 0.8738 |
| 0 | 0.043 (0.032, 0.064) | . | |||
| KLK15 | 1 | 0.132 (0.063, 0.256) | 3.263 (0.512) | 2.4–4.438 | <0.0001 |
| 0 | 0.0365 (0.006, 0.14) | . |
CI=confidence interval; KLK=kallikrein-related peptidase.
a
Back-transformed mean log ratios of cancer to normal expressions.
**P-values from the paired t-test on log-transformed values.