Table 5. Suggested therapy for arterial hypertension under tyrosine-kinase inhibitor therapy.

RR	Treatment-Free Interval	Intervention	Control	Therapy
> 140/90 mm Hg*1	No	Control within 24 h	Introduction of anti-hypertensive therapy, accompanied by repeated measurements	Frequently monotherapy, e.g. Ca antagonist or β-Blocker
Severe Hypertension (systole > 200 mm Hg*2)	Yes	Changes monitored closely, rapid escalation with exhaustion of the single dose		Mostly combination therapy. For example, additional vasodilators, urapidil, central a-agonists or AT-II inhibitors. In resistant cases, multiple combinations necessary

^*1 based on the 7th report of the JNC (20)

^*2 Authors’ recommendation