Table 1.
Number, type, and size of tumors in 64-wk-old female Sprague–Dawley rats (n = 36 per group)
| SED | PA | EX | |
| Number of rats with tumors | 23 | 22 | 14 |
| Total number of tumors | 66 | 52 | 36 |
| Tumor size (mm, mean ± SEM) | 22 ± 6 | 28 ± 10 | 12 ± 5a |
| Types (number) of tumors | Granuloma (1) Mammary cystadenoma (1) Mammary cyst (4) Neoplastic invasion of adjacent skeletal muscle (malignant; 1) Ovarian cyst (1) Thyroid carcinoma (malignant; 1) | Mammary cystadenoma (1) Mammary fibroadenoma (1) Mammary gland cyst (4) Thyroid carcinoma (malignant; 2) | Endometrial polyp (2) Mammary fibroadenoma (1) Mammary gland cyst (4) |
a
Value for EX rats significantly (P < 0.05) lower than that for SED and PA rats.