Changes in blood coagulation-related parameters in pregnant rats. Data are presented as differences from the levels in nonpregnant rats. *, P < 0.05; **, P < 0.01 compared with value from control group. PLT, platelet count; PT, prothrombin time; TBT, overall activity of vitamin-K–dependent coagulation factors; APTT, activated partial thromboplastin time; ATIII , antithrombin time.