Table 3.

Changes in blood coagulation-related parameters (mean ± 1 SD) in pregnant rats

	Fibrinogen (mg/dL)	Platelets (×104/µL)	Prothrombin time (s)	Overall activity of vitamin-K–dependent coagulation factors (s)	APTT (s)	Antithrombin time (%)
Nonpregnant	217 ± 14	114.2 ± 13.7	13.0 ± 0.5	28.91 ± 1.47	18.8 ± 1.1	147 ± 6
GD7	201 ± 23	116.8 ± 12.0	12.3 ± 0.3a	28.15 ± 1.55	16.8 ± 1.4b	142 ± 7
GD13	263 ± 40a	125.8 ± 5.1c	13.1 ± 0.6	31.68 ± 1.35b	19.2 ± 1.7	162 ± 12a
GD17	271 ± 35a	128.1 ± 12.5d	12.7 ± 0.4	27.96 ± 1.06	20.2 ± 2.5	155 ± 8d
GD20	460 ± 44a	137.7 ± 40.2	11.3 ± 0.3a	25.19 ± 0.98b	23.4 ± 1.5b	154 ± 9

APTT, activated partial thromboplastin time

^aP < 0.01 compared with value from nonpregnant animals (Aspin–Welch t test; n = 10 per group)

^bP < 0.01 compared with value from nonpregnant animals (Student t test; n = 10 per group)

^cP < 0.05 compared with value from nonpregnant animals (Aspin–Welch t test; n = 10 per group)

^dP < 0.05 compared with value from nonpregnant animals (Student t test; n = 10 per group)