Table 2. Comparison of advantages and disadvantages of ibuprofen and paracetamol in pain therapy^*1.

	Ibuprofen	Paracetamol
Advantages
	Potent analgesic	Rectal administration form also available for young children
	Wide therapeutic range	Approved for infants <6 months
	Low toxicity on overdose	No antiplatelet effect
	Palatable syrups	Intravenous formulation available
	Better tolerability in children <2 years with history of obstructive bronchitis
	Dose certainty (3 × 10 mg/kg/BW/day)
	Long duration of action (8 h)
Disadvantages
	Only approved from age 6 months	Dose uncertainty
	Risk of acute renal failure if pre-existing relevant dehydration	Narrow therapeutic range Extremely high toxicity on overdose Weak analgesic potency
		Relatively unpalatable oral formulation

^*1 5, 15, 16, 25, e19, e48–e53; BW, body weight