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Administration of α-GalCer to CD1d-deficient mice fails to protect them against sporozoite-induced P. yoelii malaria infection
| Mice | Injected with | No. of mice protected/no. of challenged | Percentage protection (no parasitemia) |
|---|---|---|---|
| C57BL/6 | |||
| CD1−/− | α-GalCer | 0/6 | 0 |
| — | 0/5 | 0 | |
| CD1+/− | α-GalCer | 5/5 | 100 |
| — | 0/4 | 0 | |
| CD1+/+ | α-GalCer | 5/5 | 100 |
| — | 0/5 | 0 | |
| BALB/c | |||
| CD1−/− | α-GalCer | 0/6 | 0 |
| — | 0/5 | 0 | |
| CD1+/+ | α-GalCer | 4/4 | 100 |
| — | 0/4 | 0 |
