TABLE 4.

Nutrient intake, serum isoflavones, serum equol, and endometrial thickness at 12 mo by treatment group

	Soy protein + isoflavones (n = 25)	Soy protein + placebo (n = 24)	Control protein + isoflavones (n = 26)	Control protein + placebo (n = 22)	P (ANOVA)
Nutrient intake
Protein (g/d)
Food sources	65.3 ± 2.21	65.3 ± 2.4	65.0 ± 3.2	67.9 ± 2.9	0.87
Supplement	15.1 ± 0.5	14.5 ± 0.8	13.9 ± 0.8	13.6 ± 0.7	0.46
Total	80.4 ± 2.3	79.8 ± 2.7	78.9 ± 3.6	81.5 ± 3.0	0.94
Calcium (mmol/d)
Food sources	20.6 ± 1.5	21.3 ± 1.5	20.4 ± 1.5	21.0 ± 1.0	0.96
Supplement	14.4 ± 1.3	12.0 ± 1.2	13.4 ± 1.4	12.1 ± 0.8	0.48
Total	35.0 ± 1.2	33.3 ± 1.4	34.0 ± 1.4	33.1 ± 1.0	0.72
Vitamin D (IU)
Food sources	137 ± 13	143 ± 20	157 ± 19	161 ± 15	0.71
Supplement	366 ± 34	305 ± 32	340 ± 35	308 ± 21	0.48
Total	503 ± 27	448 ± 36	502 ± 32	469 ± 26	0.52
Energy (MJ)2	6.08 ± 0.22	6.52 ± 0.24	6.30 ± 0.27	6.32 ± 0.27	0.66
Serum isoflavones (μmol/L)
Daidzein	1.18 ± 0.23	0.21 ± 0.11	0.87 ± 0.17	0.13 ± 0.13	0.01
Genistein	0.90 ± 0.20	0.03 ± 0.02	0.88 ± 0.18	0.01 ± 0.04	0.01
Equol from producers (n = 25)	0.145 ± 0.046	—	0.191 ± 0.061	—	0.72
Endometrial thickness (mm)	3.38 ± 0.32	4.00 ± 0.54	2.88 ± 0.21	3.19 ± 0.33	0.16
No. of observations >6	0	1	0	0
Endometrial thickness change (mm)	0.41 ± 0.22	0.86 ± 0.54	0.06 ± 0.23	−0.16 ± 0.43	0.24
No. of observations	16	11	17	13

¹Mean ± SD (all such values).

²Energy from food sources only, not supplement.